In this study, the physicochemical properties of a locally produced microcrystalline cellulose derived from premature stems of sprouts of indian bamboo bambusa vulgaris coded mccbv was evaluated and compared with a commercial grade avicel ph101. In this study, the physicochemical properties of a locally produced microcrystalline cellulose derived from premature. Safety data sheet 122000000607 drontal plus version 1. In addition to enhanced strength, silicified microcrystalline cellulose compacts exhibited greater. Microcrystalline cellulose, mcc silicified microcrystalline cellulose. Microcrystalline cellulose prepared at the 55th jecfa 2000 and published in fnp52 add 8 2000, superseding specifications prepared at the 51st jecfa 1998 and published in fnp 52 add 6. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. An adi not specified was established at the 49th jecfa 1998. Microcrystalline cellulose prepared at the 55th jecfa 2000 and published in fnp52 add 8 2000, superseding specifications prepared at the 51st jecfa 1998 and published in fnp 52 add 6 1998. Microcrystalline cellulose 9004346 2326749 not listed not listed sodium lauryl sulfate 1512 2057881 not listed not listed starch, pregelatinized 9005258 2326796 not listed not listed sucrose 57501 2003349 not listed not listed titanium dioxide 463677 2366755 not listed not listed ingredient cas number eu einecs.
Definition microcrystalline cellulose is purified, partially depolymerized. Microcrystalline cellulose 9004346 2326749 not listed titanium dioxide 463677 2366755 not listed ingredient cas number eu einecselincs list classification %. Microcrystalline cellulose is a commonly used excipient in the pharmaceutical industry. Chemicalbook provide chemical industry users with microcrystalline cellulose boiling point melting point,microcrystalline cellulose density msds formula use,if you also need to microcrystalline cellulose other information. Microcrystalline cellulose is also found in weight training products such as fusion bodybuilding zeus, a testosterone booster, eca xtreme fat burner, and six star nitric oxide to name a few. This product has been classified in accordance with the hazard criteria of the cpr and the msds contains all of the information required by the cpr. Jecfa 2017 and published in fao jecfa monographs 20 2017, superseding specifications prepared at the 55. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source, is a potential dust explosion hazard. Cellulose microcrystalline revision date 29jun2018 sara 3112 hazard categoriessee section 2 for more information cwa clean water act not applicable clean air act not applicable osha occupational safety and health administration not applicable cercla not applicable california proposition 65 this product does not contain any proposition 65 chemicals. Microcrystalline cellulose e460 is a term for refined wood pulp manufactured through plant fibre hydrolysis. Microcrystalline cellulose an overview sciencedirect topics.
Microcrystalline cellulose is the same as cellulose, except that it meets usp standards. Comparative study of powdered and microcrystalline cellulose. Sep 25, 2017 according to the research analysis, the global microcrystalline cellulose market is moderately fragmented with the presence of many global and local vendors. Microcrystalline cellulose 9004346 2326749 not listed not listed sodium lauryl sulfate 1512 2057881 not listed not listed starch, pregelatinized 9005258 2326796 not listed not listed. Portions of this monograph that are national usp text, and are not part of the harmonized text, are marked with symbols to specify this fact. The information given is designed only as a guidance for safe.
Microcrystalline cellulose 9004346 proprietary starch, pregelatinized 9005258 proprietary 4. Get more details on this report request free sample pdf microcrystalline. View or download the cellulose microcrystalline msds material safety data sheet or sds for 102331 from merck. Microcrystalline cellulose 9004346 2326749 not listed not listed nadolol 42200339 2557063 not listed not listed 1020 corn starch 9005258 2326796 not listed not listed magnesium stearate 557040 2091503 not listed not listed ingredient cas number eu einecselincs list eu classification ghs classification %. Tablets can be formed that are hard, but dissolve quickly. Microcrystalline cellulose mcc is a term for refined wood pulp and is used as a texturizer, an anticaking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. This msds has been prepared to meet the requirements of the brazilian regulatory standard 147254.
Safety data sheet 109122 microcrystalline cellulose 102 ph. Microcrystalline cellulose 9004346 2326749 not listed not listed nadolol 42200339 2557063 not listed not listed 1020. As early as 1969, safanova and klenkova had described the heterogeneous benzoylation of microcrystalline cellulose. Safety data sheet cellulose microcrystalline revision date 04mar2015 12.
Jecfa 2000 and published in combined compendium of food additive specifications, fao jecfa monographs 1, vol. The microcrystalline cellulose, obtained from the stalk of sorghum caudatum, obtained by sodium hydroxide delignification followed by sodium hypochlorite bleaching and acid hydrolysis was examined for its physicochemical and tableting properties in comparison with those of the wellknown commercial microcrystalline cellulose grade, avicel ph 101. It is believed that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is. Whatman cellulose is manufactured from cotton linters having. Microcrystalline cellulose 9004346 2326749 not listed magnesium stearate 557040 2091503 not listed ingredient cas number eu einecselincs list ghs classification % maize starch 9005258. Physicochemical properties of microcrystalline cellulose. We make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Safety data sheet in accordance with regulation eu no 4532010 109123microcrystalline cellulose 112 ph. Microcrystalline cellulose 9004346 2326749 not listed magnesium stearate 557040 2091503 not listed ingredient cas number eu einecselincs list ghs classification % maize starch 9005258 2326796 not listed additional information. The first processing plant with the annual capacity of 6,800 tonnes was built in 1962 in the united states, in the city of newark, delaware. Microcrystalline cellulose mcc, a type of cellulose that has undergone purification and partial hydrolyzation, is widely used in several industries including food production, beverage. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without a warranty of any kind, expressed or implied.
Today, it is mostly used in medical and food industry applications. Commercially mcc is produced by woody plants and purified cotton. Jrs pharma the excipient family amazon web services. The most common form is used in vitamin supplements or tablets. Microcrystalline cellulose is an ingredient found in many prescription drugs for allergies, inactive or overactive thyroid, blood pressure and other diseases. Microcrystalline cellulose 9004346 2326749 not listed ingredient cas number eu einecselincs list ghs classification % hydrogenated castor oil 8001783 2322922 not listed hydroxypropyl. Microcrystalline cellulose mcc market size statistics 2026. Show this safety data sheet to the doctor in attendance.
Safety data sheet 109122 microcrystalline cellulose 102. Requirements to be met by storerooms and receptacles. Microcrystalline cellulose mcc is a cellulosebased, powderlike product invented in the 1950s. Pdf microcrystalline cellulose, a direct compression binder. Microcrystalline cellulose mcc is a cellulose based, powderlike product invented in the 1950s. Apparently, the lower molecular mass explains the lower thermal stability of avicel cellulose. Microcrystalline cellulose is fully biodegradable and its products of degradation are more toxic. Cellulose microcrystalline skin sensitization guinea pig result. It has excellent compressibility properties and is used in solid dose forms, such as tablets. Microcrystalline cellulose 9004346 2326749 magnesium stearate 557040 2091503 ingredient cas number eu einecs list %.
Microcrystalline cellulose msds, microcrystalline cellulose. Mcc is produced by treating cellulose acquired from plant materials using conventional. Safety data sheet in accordance with regulation eu no 4532010 109123 microcrystalline cellulose 112 ph. Safety data sheet microcrystalline cellulose date prepared. Microcrystalline cellulose market size was usd 868. Microcrystalline cellulose 9004346 2326749 not listed ingredient cas number eu einecselincs list ghs classification % hydrogenated castor oil 8001783 2322922 not listed hydroxypropyl methylcellulose 9004653 not listed not listed sodium starch glycolate 9063381 not listed not listed additional information. If breathing is irregular or stops, perform artificial respiration. Nov 30, 2012 this project studies the dependence of the physical and chemical properties of powdered cellulose on their natural origin and conditions of preparation. Microcrystalline cellulose 9004346 2326749 not listed not listed nadolol 42200339 2557063 not listed not listed 1020 corn starch 9005258 2326796 not listed not listed magnesium stearate.
Cellophane is a regeneratedcellulose in thin sheets for wrapping and. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. Place about 10 mg of microcrystalline cellulose on a watch glass, and disperse in 2 ml of iodinated zinc chloride solution. A new manufacturing process for microcrystalline cellulose mcc. Proprietary ingredients indicated as hazardous have been assessed under standards for workplace. Chemicalbook provide chemical industry users with microcrystalline cellulose boiling point melting point,microcrystalline cellulose density msds formula use, if you also need to microcrystalline cellulose other information. The microcrystalline cellulose, obtained from the stalk of sorghum caudatum, obtained by sodium hydroxide delignification followed by sodium hypochlorite bleaching and acid hydrolysis was examined. Mcc is produced by treating cellulose acquired from plant materials using conventional method that is acid hydrolysis. Top 5 vendors in the global microcrystalline cellulose market. Nonwood fibre production of microcrystalline cellulose from.
Safety data sheet northwest missouri state university. Persistence and degradability persistence insoluble in water. Sds of cellulose microcrystalline, safety data sheets, cas. Microcrystalline cellulose mcc is defined as a purified, partially depolymerized nonfibrous form of cellulose. We studied the effect of chemical composition and properties of the original native cellulose on the general characteristics of the powdered and microcrystalline cellulose obtained from arboreal and herbaceous cellulose, which were prepared.
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